NomosLogic
Multi-Omic Fusion Platform

TRINITY

Where genetics meets labs meets pharmacogenomics—in one deterministic pass.

TRINITY is the fusion layer that transforms isolated data streams—DNA, blood work, medications—into a unified clinical picture. Not by guessing. By cross-referencing 1.2 million validated clinical rules in 75 seconds.

Why Fusion Matters

A genetic variant alone is a data point. An abnormal lab value alone is a data point.

When both point to the same clinical finding, that is evidence.

Most platforms analyze genomics and labs in separate silos. TRINITY was built to eliminate that gap—correlating multi-omic data against a validated rule engine to surface clinically meaningful convergence.

Three Data Streams. One Result.

Genomic Variants

COVENANT-resolved variants with three-outcome classification, quality scores, and evidence levels.

Laboratory Biomarkers

Blood panels, urinalysis, and imaging findings with reference ranges and longitudinal trends.

Pharmacogenomics

Star allele diplotypes, metabolizer phenotypes, CPIC dosing guidelines, and drug interaction alerts.

What TRINITY Does

  • Fuses genomic variants with laboratory biomarkers in a single pass
  • Cross-references 1.2 million Clinical Logic Objects (CLOs) for evidence-backed correlations
  • Generates pharmacogenomic recommendations with star alleles and PMID citations
  • Detects multi-omic convergence—where genetics and labs independently confirm the same finding
  • FHIR-native export to Epic, Cerner, and any R4-compliant EHR

Performance

75s

Fusion Time

1.2M

Clinical Rules

FHIR

Native Export

3

Data Streams Fused

Clinical Outputs

CLO Match Correlation

When a genetic variant and an abnormal biomarker both point to the same clinical finding, TRINITY highlights the convergence—elevating confidence and clinical actionability.

Pharmacogenomic Alerts

Metabolizer phenotypes mapped against the patient’s active medication list. Dosing adjustments, contraindications, and monitoring recommendations surfaced automatically.

Diagnostic Reports

FHIR DiagnosticReport bundles ready for EHR integration. Structured, coded, and signed—not PDFs that sit in a folder.

Clinical Decision Support

Findings prioritized by clinical urgency (CRITICAL → ROUTINE), evidence level (1A → 4), and actionability. Clinicians see what matters first.

Deterministic. Not Probabilistic.

TRINITY is not a machine learning model. It is a deterministic rule engine. Same patient data, same logic version, same output—every time. No hallucinations. No drift. No unexplainable results.

Every finding is traceable to a specific Clinical Logic Object with evidence attribution, PMID citation, and guideline source.

See TRINITY in Action

Multi-omic fusion that clinicians can trust—because every result is deterministic, cited, and exportable.