NomosLogic

Infrastructure

Three Engines. One Platform.

Clinical genomics infrastructure that processes complete genomes in seconds — deterministically and without hallucinations.

COVENANT

Genome Resolution Engine

Resolves complete human genomes in 28 seconds. Classifies 38,324 variants into three deterministic states: Positive, Ruled Out, and Uncertain. 100% ACMG SF v3.2 secondary findings coverage with quality thresholds of GQ≥30 and DP≥20.

28s

Resolution

38,324

Variants

100%

ACMG SF v3.2

TRINITY

Multi-Omic Fusion Platform

Fuses genomic variants with laboratory biomarkers in 75 seconds. Cross-references 1.2 million clinical rules to output pharmacogenomic recommendations with star alleles and PMID citations. FHIR-native export to Epic and Cerner.

75s

Fusion

1.2M

Clinical Rules

FHIR

Native Export

PROTEUS

Evolutionary Discovery Engine

Simulates 1,000 generations of genomic evolution in 130 seconds. Predicts drug resistance patterns via in-memory execution against 13.6 million reference assets with k-anonymity enforced at the SQL layer.

1,000

Generations

130s

Simulation

13.6M

Reference Assets

The Hardy Bridge

Nomenclature Translation Layer

A proprietary nomenclature translation layer with 497,000 enriched variant-to-phenotype mappings. Translates seamlessly between rsIDs, HGVS notation, star alleles, chromosomal coordinates, LOINC, RxNorm, and ICD-10.

497K

Mappings

7

Nomenclature Systems

23+

Pharmacogenes

$10.1M

Est. Annual Savings