Clinical Genomics Infrastructure
The Operating System
for Human Life.
Better outcomes, lower costs — healthcare that works for everyone. Complete genomes resolved in seconds, not weeks.
<30s
Genome Resolution
1.2M
Clinical Rules
497K
Hardy Bridge Mappings
The Industry Sequenced the Genome. Then It Stopped.
The cost of sequencing dropped from $3 billion to $200, but interpreting results still requires 14 days and costs thousands. This delay creates critical clinical consequences in neonatal ICU, oncology, and pharmacogenomics settings.
14-Day Diagnostic Lag
Patients in NICU and oncology wait weeks for results that should take seconds. Every day of delay is a day without optimal treatment.
Thousands Per Interpretation
Manual variant classification by genetic counselors creates bottlenecks and costs that prevent population-scale genomics.
Adverse Drug Reactions
Without pharmacogenomic guidance at point-of-care, preventable ADRs remain one of the leading causes of hospitalization.
NomosLogic closes the gap — transforming genomic data into clinical action deterministically and without hallucinations.
Three Engines
NomosLogic Solutions
COVENANT
Genome Resolution Engine
28s
Resolution Time
38,324
Variants Classified
- Classifies variants into three states: Positive, Ruled Out, Uncertain
- 100% ACMG SF v3.2 secondary findings coverage
- Quality thresholds: GQ≥30, DP≥20
- Zero hallucination architecture
TRINITY
Multi-Omic Fusion Platform
75s
Fusion Time
1.2M
Clinical Rules
- Fuses genomic variants with laboratory biomarkers
- Cross-references 1.2 million clinical rules
- Pharmacogenomic recommendations with star alleles and PMID citations
- FHIR-native export to Epic and Cerner
PROTEUS
Evolutionary Discovery Engine
1,000
Generations Simulated
130s
Simulation Time
- Simulates 1,000 generations of genomic evolution
- Predicts drug resistance patterns
- In-memory execution against 13.6 million reference assets
- k-anonymity enforced at SQL layer
Proprietary Translation Layer
The Hardy Bridge
A proprietary nomenclature translation layer with 497,000 enriched variant-to-phenotype mappings. Translates seamlessly between clinical nomenclature systems.
Named after the architect. Impossible to replicate without licensing.
Translation at Scale
Industrial-Scale Intelligence
16.8M
Reference Asset Vault
1.26M
Active Clinical Rules
497K
Hardy Bridge Mappings
<30s
Genome Resolution
<90s
Multi-Omic Fusion
362+
FDA Drug-Gene Mandates
Four Markets
Built for Every Stakeholder
Health Systems
$10M+
Est. annual savings
- Eliminates 14-day diagnostic lag in NICU, oncology, rare disease
- SMART on FHIR integration with Epic and Cerner
- Court-defensible reports with PMID traceability
Pharmacies & PBMs (COMING SOON)
362+
FDA drug-gene mandates
- Real-time prescription interception at point of fill
- CYP2D6, CYP2C19, DPYD, SLCO1B1 coverage
- Reduces adverse drug reaction liability
Health Plans
1.2M
Clinical rules applied
- Population pharmacogenomics stratification
- Automated prior authorization with genomic evidence
- Reduces preventable ADR hospitalizations
Pharma R&D
$10K–$500K
Per simulation vs $800M Phase III
- PROTEUS for trial design and resistance prediction
- Identifies PGx stratification requirements
- Accelerates rare disease discovery 40–60%
Architecture
Sovereign by Design
Data Sovereignty
Patient data never leaves the database. Clinical logic executes within the PostgreSQL query planner.
Zero-Knowledge Protocol
HIPAA compliant with salted HMAC-SHA256. Identity verification without data exposure.
SOC 2 Ready
AWS Graviton3/Nitro architecture with k-anonymity enforced at the SQL layer.
Cryptographic Audit Trail
Every clinical decision is signed and traceable. Court-defensible by design.
See It Live
We don't have a pitch deck. We have a live platform. Give us 60 minutes and we'll show you something nobody else has.